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2-[(tert-butoxycarbonyl)amino]-5-hydroxybenzoic acid

2-[(tert-butoxycarbonyl)amino]-5-hydroxybenzoic acid

CAS: 244765-00-2

Molecular Formula: C12H15NO5

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2-[(tert-butoxycarbonyl)amino]-5-hydroxybenzoic acid - Names and Identifiers

Name 2-[(tert-butoxycarbonyl)amino]-5-hydroxybenzoic acid
Synonyms N-BOC-5-HYDROXYANTHRANILIC ACID
2-tert-Butoxycarbonylamino-5-hydroxybenzoic acid
2-[N-(tert-butoxy)forMaMido]-5-hydroxybenzoic acid
2-[(tert-butoxycarbonyl)amino]-5-hydroxybenzoic acid
2-[(tert-Butoxycarbonyl)amino]-5-hydroxybenzoic acid
Benzoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-5-hydroxy-
CAS 244765-00-2
InChI InChI=1/C12H15NO5/c1-12(2,3)18-11(17)13-9-5-4-7(14)6-8(9)10(15)16/h4-6,14H,1-3H3,(H,13,17)(H,15,16)

2-[(tert-butoxycarbonyl)amino]-5-hydroxybenzoic acid - Physico-chemical Properties

Molecular FormulaC12H15NO5
Molar Mass253.25
Density1.337±0.06 g/cm3(Predicted)
Boling Point385.6±37.0 °C(Predicted)
Flash Point187°C
Vapor Presure1.23E-06mmHg at 25°C
pKa3.58±0.36(Predicted)
Storage Condition2-8℃
Refractive Index1.601

2-[(tert-butoxycarbonyl)amino]-5-hydroxybenzoic acid - Introduction

2-[(tert-butoxycarbonyl)amino]-5-hydroxybenzoic acid is an organic compound, also known as Boc-amino acid. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White solid
-Molecular formula: C13H17NO4
-Molecular weight: 247.28g/mol
-Melting Point: about 125 ° C
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and dimethylformamide, insoluble in water.
-Chemical properties: The compound has the structural characteristics of amide and hydroxy acid, which can be converted into 2-amino-5-hydroxybenzoic acid through hydrolysis reaction.

Use:
-Commonly used in the field of organic synthesis as a precursor compound of a protecting group (Boc protecting group). The protecting group can be removed by chemical reaction to give the desired functional group.
-Widely used in peptide and protein synthesis to protect the α-amino group of amino acids to prevent accidental substitution or reaction during the reaction.
-In drug development, it can be used to synthesize new drug molecules.

Method:
-2-[(tert-butoxycarbonyl)amino]-5-hydroxybenzoic acid can be produced by reacting 2-amino-5-hydroxybenzoic acid with tert-butyl isocyanate.

Safety Information:
-The compound may be irritating to the skin and eyes, please pay attention to safe operation.
-Wear appropriate protective equipment such as lab gloves and goggles to avoid contact and inhalation during use.
-Follow proper operating procedures and proper laboratory safety measures, such as operating in a well-ventilated environment.
Last Update:2024-04-09 15:17:56
2-[(tert-butoxycarbonyl)amino]-5-hydroxybenzoic acid
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: ANTHRANILIC ACID, N-BOC-5-HYDROXY Visit Supplier Webpage Request for quotation
CAS: 244765-00-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: 2-tert-Butoxycarbonylamino-5-hydroxybenzoic acid Visit Supplier Webpage Request for quotation
CAS: 244765-00-2
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: ANTHRANILIC ACID, N-BOC-5-HYDROXY Visit Supplier Webpage Request for quotation
CAS: 244765-00-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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